The cardiovascular system, especially heart muscle, is extremely metabolically active. Maintaining sufficient NAD+ levels is important to good heart function and reducing oxidative stress. NAD+ also supports the health of blood vessels, promoting nitric oxide signaling, which tells blood vessels to dilate, and helping to maintain healthy blood pressure levels.

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A study on middle-aged and older adults with above-normal blood pressure found that NAD+ supplementation effectively lowered systolic blood pressure and reduced arterial stiffness. This is a significant finding because even a small reduction in blood pressure can lower the risk of cardiovascular events.

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NAD+ supplementation reduces levels of homocysteine, a key biomarker for cardiovascular disease

Homocysteine is an amino acid that our cells naturally produce as a byproduct of metabolism. For decades, elevated homocysteine has been used as a valuable biomarker and a risk factor for cardiovascular disease. High homocysteine levels are thought to indicate damage to the lining of blood vessels (the endothelium), inflammation, and risk for the buildup of arterial plaques, all key mechanisms contributing to blood clots and heart disease.

 

Cardiovascular health is closely tied to other body systems, especially the brain. Accordingly, high homocysteine levels are also associated with risk for dementia and Alzheimer’s Disease.

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The body uses the B vitamins folate, B6, and B12 to convert homocysteine into other useful compounds. Our supplement is specially formulated to support metabolism of homocysteine, helping to prevent these recycling pathways from becoming compromised and from homocysteine to build up.

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